A split-thickness skin graft involves taking a thin layer of skin from one part of the body (usually the thigh) and using it to reconstruct another area that has lost skin or tissue. In laryngology, it may be used to cover large mucosal defects in the throat, trachea, or neck following tumor removal or trauma.

The surgery is performed under general anesthesia. The graft is harvested, placed over the defect, and then secured with fine sutures or tissue glue. A dressing or stent may be used to protect the area during healing. Recovery can vary depending on the size and location of the graft, but patients may need voice rest, antibiotics, and regular monitoring to ensure graft success. The donor site typically heals in 1–2 weeks and may feel like a scrape or mild burn. Graft survival is usually excellent when kept moist and undisturbed.